Christina graduated from Georgetown University, her mother Maria Shriver's alma mater, in 2013 with a bachelor's degree in English. She then worked as an editor at Gwyneth Paltrow's lifestyle brand, Goop, covering health and wellness topics.

She's also collaborated with her mother to produce two documentaries: Take Your Pills (2018) and Take Your Pills: Xanax (2022). The first documentary delves into Christina's personal experiences with Adderall addiction.

Christina is a founding member of the Special Olympics Founder's Council; her grandmother, Eunice Kennedy Shriver, founded the Special Olympics in 1968. Reflecting on her involvement with the organisation, Christina once stated: "I love shining a light on those who feel outside the margins and bringing their experiences to light. The result is that we all feel validated and, ultimately, see that our differences are in fact our superpowers."

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